Search results for "Unclassified drug"

showing 10 items of 20 documents

Metabolic shift of polyphosphate-accumulating organisms with different levels of polyphosphate storage

2012

Previous studies have shown that polyphosphate-accumulating organisms (PAOs) are able to behave as glycogen-accumulating organisms (GAOs) under different conditions. In this study we investigated the behavior of a culture enriched with Accumulibacter at different levels of polyphosphate (poly-P) storage. The results of stoichiometric ratios Gly degraded/HAc uptake, PHB synthesized/HAc uptake, PHV synthesized/HAc uptake and P release/HAc uptake confirmed a metabolic shift from PAO metabolism to GAO metabolism: PAOs with high poly-P content used the poly-P to obtain adenosine tri-phosphate (ATP), and glycogen (Gly) to obtain nicotinamide adenine dinucleotide (NADH) and some ATP. In a test whe…

Accumulibacter Type IIWaste component removalUnclassified drugPhysiologyChemical compositionMicrobial metabolismStorageWastewaterNicotinamide adenine dinucleotidePolyhydroxyalkanoic acidchemistry.chemical_compoundBacteriumBioreactorsPolyphosphatesGlycolysisAnaerobiosisBiomassPolyphosphate-accumulating organismsWaste Management and DisposalAccumulibacter Type IGlycogen accumulating organismPriority journalWater Science and TechnologyFluorescence microscopyPolyhydroxyvalerateSewageGlycogenHydrolysisFluorescence in situ hybridizationEcological ModelingPhosphorusHydrogen-Ion ConcentrationBioaccumulationPollutionStoichiometryWaste treatmentPolyphosphate-accumulating organismsBiodegradation EnvironmentalEnhanced biological phosphorus removalBiochemistryGlycogen-accumulating metabolism (GAM)Nicotinamide adenine dinucleotideAccumulibacter type 1Accumulibacter type 2GlycolysisGlycogenMetabolic Networks and PathwaysAccumulibacterAdenosine triphosphateEnvironmental EngineeringBiologyAcetic acidArticleAssociative storagePolyphosphate-accumulating metabolism (PAM)PolyphosphateGlycogen-accumulating organismsGlycogen-accumulating metabolismsTECNOLOGIA DEL MEDIO AMBIENTEPolyphosphate accumulating organismCivil and Structural EngineeringPolyphosphate-accumulating organisms (PAO)BacteriaPolyphosphateMetabolismIn situ measurementGlycogen-accumulating organisms (GAO)Polyphosphate-accumulating metabolismsNonhumanAmidesCarbonMetabolismchemistryPolyphosphate (poly-P)Bacterial metabolismCell cultureVolatilizationWater Research
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Distinct photodynamics of κ-N and κ-C pseudoisomeric iron(ii) complexes

2021

Two closely related FeII complexes with 2,6-bis(1-ethyl-1H-1,2,3-triazol-4yl)pyridine and 2,6-bis(1,2,3-triazol-5-ylidene)pyridine ligands are presented to gain new insights into the photophysics of bis(tridentate) iron(II) complexes. The [Fe(N^N^N)2]2+ pseudoisomer sensitizes singlet oxygen through a MC state with nanosecond lifetime after MLCT excitation, while the bis(tridentate) [Fe(C^N^C)2]2+ pseudoisomer possesses a similar 3MLCT lifetime as the tris(bidentate) [Fe(C^C)2(N^N)]2+ complexes with four mesoionic carbenes. Financial support from the Deutsche Forschungsge-meinschaft [DFG, Priority Program SPP 2102] "Light-controlled reactivity of metal complexes" (BA 4467/7-1, LO 714/11-1, …

TrisDenticitysynthesisPyridinepyridine derivativecarbenoidIron compoundsCatalysisexperimental studychemistry.chemical_compoundPyridineMaterials Chemistryphysical chemistrycontrolled studyChemistrySinglet oxygenPyridine ligandsSinglet oxygenMetals and AlloysMesoionicGeneral ChemistryNanosecondPyridine ligandSurfaces Coatings and FilmsElectronic Optical and Magnetic Materialsunclassified drugCrystallographyPhotophysicsiron complexisomerCeramics and CompositesCarbeneschemical structurephotodynamicsphysicsExcitationchemical parameters
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Nerve agent simulant detection by using chromogenic triaryl methane cation probes

2012

Two triaryl methane cations have been used as probes for colorimetric detection of nerve agent simulants. Buffered mixed aqueous solutions of 1 and 2 showed bathochromic shifts in the presence of DCNP (diethylcyanophosphonate) and DCP (diethylchlorophosphate). The colour modulation can be observed to the naked eye. Appropriate mechanisms for the recognition event are proposed. © 2012 Elsevier Ltd.

Unclassified drugInorganic chemistryBiochemistryMethanechemistry.chemical_compoundChromogenicQUIMICA ORGANICADrug DiscoveryBathochromic shiftmedicineAqueous solutionTriaryl methane cationColorimetryNerve agentAqueous solutionChromogenicChemistryChemical warfare agentOrganic ChemistryQUIMICA INORGANICAChemical warfareChemosensorTriaryl methane dyeColorimetryNaked eyemedicine.drug
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Highly selective and sensitive chromo-fluorogenic detection of the Tetryl explosive using functional silica nanoparticles

2011

Silica nanoparticles containing polyamines and thiol groups have been used as probes for the selective detection of Tetryl. © 2011 The Royal Society of Chemistry.

PolyamineINGENIERIA DE LA CONSTRUCCIONUnclassified drugNanoparticlePhotochemistryColorimetry (chemical method)Nitrobenzenechemistry.chemical_compoundNanoparticleQUIMICA ORGANICAChemical structureSilicon dioxidePolyaminesMaterials ChemistryChemical analysischemistry.chemical_classificationAniline CompoundsChemistryMetals and Alloysrespiratory systemTetrylSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsThiolColorimetryDyeExplosive materialSilicon dioxideChemical structureArticleCatalysisThiol groupBinding site246 trinitrophenylmethylnitramineExplosive AgentsExplosiveReaction analysisQUIMICA ANALITICASulfhydryl CompoundsNitrobenzenesSensorFluorescent DyesFluorescent dyeQUIMICA INORGANICAGeneral ChemistrySilane derivativeCombinatorial chemistryChromogenic substrateCeramics and CompositesNanoparticlesChemical Communications
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Chemical composition and herbicidal activity of the essential oil from a Cistus ladanifer population from Spain

2012

[EN] The essential oil composition of Cistus ladanifer grown in central Spain was analysed by gas chromatography and gas chromatography/mass spectrometry, revealing it to be rich in oxygenated compounds, with trans-pinocarveol (20.00%), bornyl acetate (7.03%) and terpinen-4-ol (6.37%) as the main monoterpene compounds. Viridiflorol (13.59%) and ledol (4.36%) were the main constituents of the oxygenated sesquiterpene fraction. Large amounts of-pinene (4.70%) were found in the hydrocarbonated fractions. To study its possible use as a natural herbicide, the oil was tested invitro against Amaranthus hybridus, Portulaca oleracea, Chenopodium album, Conyza canadensis and Parietaria judaica, compl…

SesquiterpeneHerbicidal activityLedolUnclassified drugAmaranthus hybridusPineneTerpinen 4 olChemical compositionAmaranthus hybridusPlant ScienceBiochemistryCistus ladaniferEssential oilAnalytical Chemistrylaw.inventionChenopodium albumchemistry.chemical_compoundLedollawBornyl acetateBicyclic MonoterpenesBIOLOGIA VEGETALeducation.field_of_studyAmaranthusbiologyGC/MSCistusPortulacaceaeConyza canadensisGerminationCistus ladaniferPinocarveolHerbicideTerpene derivativeChromatography GasPopulationBOTANICAMass fragmentographyGerminationPortulacaArticleGas Chromatography-Mass SpectrometryChenopodiumCistusBotanyOils VolatileeducationEssential oilHerbicidesOrganic ChemistryTerpinen-4-olCistaceaebiology.organism_classificationWeedParietaria judaicaParietariachemistrySpainViridiflorolMonoterpenesWeedsConyza
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Drug‐refractory myasthenia gravis: Clinical characteristics, treatments, and outcome

2022

[Objective] To describe the clinical characteristics and outcomes in patients with refractory myasthenia gravis (MG) and to determine the effectiveness and side effects of the drugs used for their treatment.

Maleprogressive multifocal leukoencepdiarrheacholinergic receptorplasma exchangemiddle agedadultimmunologic factornauseaanemiahypertrichosisageddrug withdrawaldiabetes mellitusdisease severityTRIALsafetycorticosteroidhypertensionImmunologyMiastenia gravismethotrexateArticlebulbar paralysispancytopeniaMuscular DiseasescompulsionMyasthenia Gravischolinesterase inhibitorcross-sectional studyHumansImmunologic FactorshumanRITUXIMABarthralgiaNeurologíaMalalties muscularsAgedRetrospective Studiesmyasthenia gravisleukopeniaabdominal painDrug testingmajor clinical studyCross-Sectional StudiesDrug side effectscyclophosphamideobservational studyNeurology (clinical)immunoglobulinFEATURESefficacyclinical outcomeelectrophysiological procedurescomputer assisted tomographyDOUBLE-BLINDTratamiento médicorituximabOutcome Assessment Health CareImmunologiamuscle specific tyrosine kinaseRegistriestacrolimusazathioprineMedicamentoGeneral Neurosciencenephrotoxicitygeneral condition deteriorationhyperplasiatrialMiddle Agedliver toxicitydrug toxicityunclassified drugfemaleEfectes secundaris dels medicamentsSAFETYFemaledouble-blindheadacheblindnessAdultAssaigs clínics de medicamentsmalefeaturesfollow uppneumoniacyclosporinemycophenolate mofetilprotein tyrosine kinaseimmunosuppressive agentallergyalopeciaEFFICACYclinical featureosteopeniaSpainprednisonehyperglycemiaautoantibodyFollow-Up Studies
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Increased conformational rigidity of humic substances by oxidative biomimetic catalysis

2005

A synthetic water-soluble meso-tetra(2,6-dichloro-3-sulfonatophenyl)porphyrinate of iron(III) chloride, Fe(TDCPPS)Cl, was employed as a biomimetic catalyst in the oxidative coupling of terrestrial humic materials. High-performance size-exclusion chromatography (HPSEC), solid-state nuclear magnetic resonance (CPMAS-(13)C NMR), electron paramagnetic resonance (EPR), and diffuse reflectance infrared spectroscopy (DRIFT) were used to follow conformational and structural changes brought about in different humic materials by the oxidative coupling. Increase in apparent weight-average molecular weight (Mw(a)) occurred invariably for all humic substances with the oxidative polymerization catalyzed …

conformationMagnetic Resonance SpectroscopySpectrophotometry InfraredPolymers and PlasticsDiffuse reflectance infrared spectroscopy (DRIFT)Biomimetic materialsaromatic compoundgel permeation chromatographyMolecular ConformationPhotochemistryIron compoundslaw.inventionPolymerizationenvironmental managementcovalent bondlawSize exclusion chromatographyBiomimetic catalysisBiomimeticsMaterials ChemistryOrganic chemistryHumic acidElectron paramagnetic resonanceInfrared spectroscopyChromatography High Pressure Liquidchemistry.chemical_classificationSettore CHIM/03 - Chimica Generale e InorganicaCarbon IsotopesChromatographyindustryCatalystsChemistrytetra(2articleelectrophoretic mobilitybiomimetic materialNuclear magnetic resonance spectroscopyunclassified drugConformationsacetic acidpriority journalCovalent bondSpectrophotometrySynthesis (chemical)High Pressure Liquidtechnology6 dichloro 3 sulfonatophenyl)porphyrinic acid derivativeInfraredOxidation-Reductionmolecular stabilityHumic materialsoxidationSettore AGR/13 - Chimica AgrariaSupramolecular chemistryBioengineeringcomplex mixturesCatalysisCatalysisdiffuse reflectance spectroscopyhumic substanceBiomaterialsalkyl etherElectron spin resonance spectroscopycomplex formationParticle SizeNuclear magnetic resonance spectroscopyHumic Substancesfree radicalbiomimetic oxidative humicelectron spin resonanceHigh performance size exclusion chromatography (HPSEC)ferrous chloridemolecular weightsolid statecarbon nuclear magnetic resonancePolymerizationSolubilitychemical structureOxidative coupling of methaneCatalysts; Conformations; Electron spin resonance spectroscopy; Infrared spectroscopy; Iron compounds; Nuclear magnetic resonance spectroscopy; Oxidation; Polymerization; Size exclusion chromatography; Solubility; Synthesis (chemical); Biomimetic catalysis; Diffuse reflectance infrared spectroscopy (DRIFT); High performance size exclusion chromatography (HPSEC); Humic materials; Biomimetic materials; acetic acid; alkyl ether; aromatic compound; biomimetic material; ferrous chloride; free radical; tetra(26 dichloro 3 sulfonatophenyl)porphyrinic acid derivative; unclassified drug; article; carbon nuclear magnetic resonance; catalysis; catalyst; chemical structure; complex formation; conformation; covalent bond; diffuse reflectance spectroscopy; electron spin resonance; electrophoretic mobility; environmental management; gel permeation chromatography; humic substance; industry; molecular stability; molecular weight; oxidation; polymerization; priority journal; solid state; technology; Biomimetics; Carbon Isotopes; Catalysis; Chromatography High Pressure Liquid; Electron Spin Resonance Spectroscopy; Humic Substances; Magnetic Resonance Spectroscopy; Molecular Conformation; Oxidation-Reduction; Particle Size; Spectrophotometry Infraredcatalyst
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Cellular effects of bacterial N-3-Oxo-dodecanoyl-L-Homoserine lactone on the sponge Suberites domuncula (Olivi, 1792): insights into an intimate inte…

2014

International audience; Sponges and bacteria have lived together in complex consortia for 700 million years. As filter feeders, sponges prey on bacteria. Nevertheless, some bacteria are associated with sponges in symbiotic relationships. To enable this association, sponges and bacteria are likely to have developed molecular communication systems. These may include molecules such as N-acyl-L-homoserine lactones, produced by Gram-negative bacteria also within sponges. In this study, we examined the role of N-3-oxododecanoyl-L-homoserine lactone (3-oxo-C12-HSL) on the expression of immune and apoptotic genes of the host sponge Suberites domuncula. This molecule seemed to inhibit the sponge inn…

ProteomicsApoptosisPathogenesisPathology and Laboratory MedicineBiochemistrycaspase 74-Butyrolactonecaspase 3lcsh:ScienceCytoskeletoncaspase like 7 gene0303 health sciencesToll-like receptorMarine Ecologytoll like receptorGenomicsproto oncogeneEndocytosisCell biologySuberites domunculaCellular Structures and Organellesalpha actininCell signalingtoll like receptor associated factor 6Gram negative bacteriumparacrine signalingMicrobiology03 medical and health sciencesGeneticsRNA Messengerhost pathogen interactionprotein expressiontwo dimensional electrophoresisBacteria030306 microbiologyEcology and Environmental Scienceslcsh:RBiology and Life SciencesComputational BiologyImmunity Innatecarrier proteinSpongebacterial membranelcsh:Qimmunological toleranceSuberitesProtein AbundanceSuberitessuberites domuncula[SDV]Life Sciences [q-bio]lcsh:MedicineMolecular Cell BiologyMedicine and Health Sciencesinnate immunityperforinMultidisciplinaryEcologybiologymessenger RNAarticlecell communicationAnimal Modelsmatrix assisted laser desorption ionization time of flight mass spectrometryunclassified drugPoriferaHost-Pathogen InteractionscytotoxicityactinTranscriptome Analysishormone actionResearch ArticleSymbiotic bacteriaprotein bcl 2Marine BiologycofilinResearch and Analysis Methodsn (3 oxododecanoyl)homoserine lactoneMicrobial EcologycogninModel OrganismsHomoserineAnimalscontrolled study14. Life underwatergeneSymbiosiscell viabilityadenosine triphosphatase030304 developmental biologynonhumanChemical EcologyMembrane ProteinsCell Biologytumor necrosis factor receptor associated factor 6Genome Analysisbiology.organism_classificationalpha tubulinGene Expression RegulationMembrane proteingene expressioncaspase like 3 geneGenome Expression AnalysisBacteriaPLoS ONE
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On the formation of inclusion complexes at the solid/liquid interface of anchored temperature-responsive PNIPAAM diblock copolymers with γ-cyclodextr…

2017

The thermal responsive behavior of adsorbed layers of diblock copolymers of poly(N-isopropylacrylamide) (PNIPAAM) and poly((3-acrylamidopropyl)trimethylammonium chloride) (PAMPTMA(+)) with γ-cyclodextrin (γ-CD) at the solid/liquid interface has been investigated using three in situ techniques: null ellipsometry, quartz–crystal microbalance with dissipation monitoring, and neutron reflectometry. The measurements provided information about the adsorbed amounts, the layer thickness, hydration and viscoelastic properties, and the interfacial structure and composition. The copolymers adsorb to silica with the cationic PAMPTMA(+) blocks sitting as anchors in a flat conformation and the PNIPAAM ch…

AmidePolymers and PlasticsBlock copolymerReflectometerReflection02 engineering and technology01 natural sciencessupramolecular chemistryquartz crystal microbalancechemistry.chemical_compoundColloid and Surface ChemistryEllipsometryViscoelasticity Inclusion complexCopolymerMaterials ChemistryPoly (n isopropylacrylamide)Poly(N-isopropylacrylamide)Settore CHIM/02 - Chimica Fisicachemistry.chemical_classification/dk/atira/pure/subjectarea/asjc/1600/1606Reflectometry/dk/atira/pure/subjectarea/asjc/1500/1505Cyclodextrinunclassified drug Article021001 nanoscience & nanotechnologyThermoresponsive block copolymerpriority journalsolidpolymerizationPoly(N-isopropylacrylamide)synthesiNeutron reflectometrypolyrotaxane0210 nano-technologyellipsometryMaterials science/dk/atira/pure/subjectarea/asjc/2500/2505/dk/atira/pure/subjectarea/asjc/2500/2507poly(n isopropylacrylamide)010402 general chemistryLower critical solution temperatureAcrylic monomeratom transfer radical polymerizationAdsorptioncomplex formationPolymer chemistryCyclodextrinliquidPhysical and Theoretical ChemistrySolid/liquid interfaceThermo-responsive Hydrogels copolymerneutron reflectometryInclusion complexgamma cyclodextrinCationic polymerization0104 chemical sciencessolid liquid interfacechemistryChemical engineeringInvited ArticleColloid and Polymer Science
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Micropollutants removal in an anaerobic membrane bioreactor and in an aerobic conventional treatment plant

2012

The paper expresses an attempt to tackle the problem due to the presence of micropollutants in wastewater which may be able to disrupt the endocrine system of some organisms. These kinds of compounds are ubiquitously present in municipal wastewater treatment plant (WWTP) effluents. The aim of this paper is to compare the fate of the alkylphenols-APs (4-(tert-octyl)) phenol, t-nonylphenol and 4-p-nonylphenol and the hormones (estrone, 17ß-estradiol and 17¿-ethinylestradiol) in a submerged anaerobic membrane bioreactor (SAMBR) pilot plant and in a conventional activated sludge wastewater treatment plant (CTP). The obtained results are also compared with the results obtained in a previous stud…

INGENIERIA HIDRAULICAUnclassified drugEffluentsExtractionEstrogenic hormonesOxic conditionsMembrane bioreactorDegradationBioreactorsEndocrinologyChemical structureLimit of Detection(4 (tert octyl)) phenolWater PollutantsAnaerobiosisWater Science and TechnologyPilot plantsWaste water managementEstradiolChemistryMembranePhenol derivativeWater samplingPulp and paper industryWaste treatmentEndocrine disruptorWastewaterPollutant removalMembrane bioreactorSewage treatmentActivated sludge plantsAnaerobic exerciseAnaerobic membrane bioreactorActivated sludge plantChromatography GasEnvironmental EngineeringWaste water treatment plantHydraulic retention timeEstroneBioreactorMass fragmentographyPollutantSewage pumping plantsArticlePhenolsEthinylestradiolBioreactorWater treatment plantsEffluentSolid Phase MicroextractionTECNOLOGIA DEL MEDIO AMBIENTE3 nonylphenolChromatography4 nonylphenolAlkylphenol polyoxyethyl etherMembranes ArtificialAlkylphenolsHormoneHormonesActivated sludgeActivated sludgeAnoxic conditionsWater Science and Technology
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